Assumptions regarding event probabilities | Impact§ |
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We applied osteoporosis prevalence rates and BMD-values from US-NHANES III reference data | *** |
We estimated “total” fracture probabilities by dividing fracture probabilities based on hospital cases with age-independent hospital probabilities | ** |
We assumed highest fracture related NH probability when more than one fractures occurs in the same time interval | ** |
We modeled fracture related entry in a NH only after a hospital stay | ** |
We assumed that only NH entries within 3 months after a fracture may be attributable to the fracture event itself | ** |
We applied age-dependent relative fracture risk by one standard deviation decrease in BMD to hip fractures and age-independent relative risks to other fractures | ** |
We assumed that osteoporosis risk attributions were calculated exclusively on BMD values measured at the femoral neck | ** |
We assumed that osteoporosis prevalence rates do not differ between women living in a NH and women who do not | * |
We applied relative fracture risk and prevalence for previous fractures from an international meta-analysis | * |
We applied relative fracture risk by one standard deviation decrease in BMD from international studies | * |
We applied fracture mortality data from a Canadian study | * |
We assumed the highest fracture excess mortality when more than one fracture occurs in the same time interval | * |
We allowed first entry in a NH firstly for women aged 65 or older | * |
We assumed that individuals in a NH remain there for their remaining lifetime | * |
We assumed that patients with osteoporosis will have osteoporosis for their remaining lifetime | * |
We allowed a maximum possible age of 100 years | * |
Assumptions regarding costing | |
We assumed that rehabilitation probabilities after a hospital stay do not differ between women living in NH and those who do not. | ** |
We applied Austria data for average hours of informal and professional home care by fracture type, also we assumed that the consumed hours are equivalent for hip, other femur and pelvis | ** |
We assumed age-dependent fracture unit costs | * |
We assumed that the outpatient costs for humerus and wrist as well as the costs for pelvis, other femur and hip fractures are equivalent | * |
We took outpatient resource use data from a study considering fracture patients with inflammatory bowel disease | * |
We assumed that average informal and professional home care costs are only applicable for individuals not living in NH aged older than 65 years | * |