Table 2 Unit and monthly cost of mCRPC medications

Primary medication

Bicalutamide (Casodex)

1 × 50 mg daily

[17]

$1.61 per tablet (50 mg)

[42]

$58.71

Abiraterone (Zytiga)

4 × 250 mg daily

[34]

$28.3333 per tablet (250 mg)

[42]

$3,448

Cabazitaxel (Jevtana)

25 mg/m² i.v. every 21 days

[36]

$5,840 per vial (60 mg/1.5 ml)

[46]

$8,460^*

Docetaxel (Taxotere)

75 mg/m² i.v. every 21 days

[26]

$599.79 per vial (160 mg/16 ml)^**

[46]

$774^*

Prednisone (Deltasone)

2 × 5 mg daily

[34]

$0.022 per tablet (5 mg)^**

[42]

$1.34

Premedication for chemotherapy-induced side effects

Dexamethasone^†‡

8 mg i.v. every 21 days

[26, 36]

$3.24 per vial (10 mg/ml, 1 ml)^**

[46]

$4.69

Diphenhydramine^†

25 mg i.v. every 21 days

[36]

$2.98 per vial (50 mg/ml, 1 ml)^**

[46]

$4.32

Famotidine^†

20 mg i.v. every 21 days

[36]

$2.71 per vial (10 mg/ml, 2 ml)^**

[46]

$3.93

Medication for medical castration

Goserelin (Zoladex)

10.8 mg s.c. every 3 months (13 weeks)

[40]

$1,113 per 10.8 mg depot 3 months

[42]

$371

Bone-targeted therapy

Denosumab (XGEVA)

120 mg s.c. every 4 weeks

[23]

$538.45 per vial (120 mg/1.7 ml)

[42]

$585