Table 5 Patient activity as a proxy for survival: role of patient and institutional factors in CML patients (multivariate Cox model)

Patient covariates

 Age

<55y

1 (ref)

> = 55y

1.42

0.001

[1.16; 1.73]

 Initial phase

Chronic

1 (ref)

Accelerated form or blast crisis

4.16

<10^-4

[1.87; 9.25]

Institutional covariates

 Research ability

0.55

0.01

[0.35; 0.86]

 Public institution

1.32

0.10

[0.95; 1.84]

 ≥1 hematologist or oncologist

0.88

0.73

[0.44; 1.79]

 Enrollment

<2 patients enrolled/y

1(ref)

[2–5] patients enrolled/y

0.69

0.09

[0.45; 1.07]

>5 patients enrolled/y

0.48

<10^-4

[0.35; 0.67]

Interaction

 Accelerated form * ≥1 hematologist or oncologist

0.43

0.05

[0.18; 0.99]