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Table 5 Summary of parameter distributions for costs (in 2010 euros) used in the PSA

From: A multi-perspective cost-effectiveness analysis comparing rivaroxaban with enoxaparin sodium for thromboprophylaxis after total hip and knee replacement in the German healthcare setting

Costs of resources

Parameter

Expected costs (€) (standard error)

  

After THR

After TKR

  

Hospital perspective

SHI perspective

Hospital perspective

SHI perspective

Prophylaxis costs with enoxaparin in the case of

Post-discharge VTE or no VTE and no MB

par_14

0

106.42 (10.64)

0

1.63 (0.16)

Prophylaxis costs with rivaroxaban in the case of

MB with or without VTE

par_15

13.00 (1.30)

0

13.00 (1.30)

0

Pre-discharge VTE without MB

par_16

18.20 (1.82)

0

18.20 (1.82)

0

Post-discharge VTE or no VTE and no MB

par_17

32.24 (3.22)

134.85 (13.49)

33.02 (3.30)

2.06 (0.21)

Total costs of pre-discharge VTE

DVT

par_18

1,282.27 (128.33)

157.35 (17.74)

1,115.14 (111.51)

157.40 (15.74)

Non-fatal PE

par_19

2,105.22 (210.52)

157.23 (15.73)

2,362.79 (236.28)

348.40 (34.84)

Total costs of post-discharge VTE

     

DVT

par_20

0

1,995.89 (199.59)

0

1,995.89 (199.59)

Non-fatal PE

par_21

0

3,700.43 (370.04)

0

3,700.43 (370.04)

Fatal PE

par_22

0

1,256.43 (125.64)

0

1,256.43 (125.64)

  1. PSA = probabilistic sensitivity analysis, THR = total hip replacement, TKR = total knee replacement, SHI = social health insurance, VTE = venous thromboembolism, MB = major bleeding, DVT = deep vein thrombosis, PE = pulmonary embolism.